A deadly virus known as Death 1 Compound is snatched from a research lab but the virus is released during the thief’s escape. He is infected (surprise surprise) and turns into a flesh eating zombie. He holes up in a local hotel and spreads the virus. The army come in and kill everybody that is contaminated. However they burn the bodies and the ashes are released and react with the air.
Meanwhile three off duty soldiers meet up with and save a camper van of (supposedly) attractive women who have been attacked by zombified birds. Instead of heading to a hospital they decide that the local hotel is a better bet. Which hotel, you guessed it, the same one that just cleared out its zomboid flesh digesting infestation. From there on in the survivors have to deal with wave after wave of zombies as well as the army who are under orders to kill everything in the contaminated area. The few left living realise the predicament they are in but vow to fight on.